Prion diseases

被引：19

作者：

Collinge, John ^{[1
]}

Palmer, Mark S. ^{[1
]}

机构：

[1] St Marys Hosp, Med Sch, Dept Biochem & Mol Genet, London W2 1PG, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1992年 / 2卷 / 03期

关键词：

D O I：

10.1016/S0959-437X(05)80156-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

There have been remarkably rapid advances in the understanding of prion diseases over the past year. The controversial notion that the transmissible agent may be an abnormal isoform of a host-encoded protein, the prion protein, is now gaining wide acceptance. The conundrum of how a disease can both be inherited as an autosomal dominant condition and also be experimentally transmissible by inoculation is beginning to make sense.

引用

页码：448 / 454

页数：7

共 36 条

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