IGE-MEDIATED ALLERGY TO WOOD DUSTS PROBABLY DOES NOT EXPLAIN THE HIGH PREVALENCE OF RESPIRATORY SYMPTOMS AMONG SWEDISH WOODWORK TEACHERS

被引:17
作者
AHMAN, W
VANHAGEHAMSTEN, M
JOHANSSON, SGO
机构
[1] KAROLINSKA INST,DEPT MED,DIV ENVIRONM & OCCUPAT MED,S-14186 HUDDINGE,SWEDEN
[2] KAROLINSKA HOSP,DEPT LAB MED,DIV CLIN IMMUNOL,S-17176 STOCKHOLM,SWEDEN
关键词
ALLERGY; IGE; OCCUPATIONAL EXPOSURE; RAST; WOOD DUST;
D O I
10.1111/j.1398-9995.1995.tb01199.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
A previous study revealed an increased occurrence of work-related respiratory complaints among Swedish woodwork teachers. For determination of whether an IgE-mediated mechanism was the cause of the symptoms, 127 woodwork teachers and 111 reference subjects (other school personnel) in Stockholm gave serum for analysis of total IgE, Phadiatop, and RAST to extract of sawdust from five commonly used Scandinavian woods (pine, birch, juniper, alder, and linden). The total serum-IgE level was similar in the woodwork teachers (geometric mean 35, range <2-1700 kU/l) and the reference group (34, <2-860 kU/l), and the frequency of positive Phadiatop was equal (29.9% and 31.5%, respectively). RAST was positive only in three cases, two reference subjects (birch and pine) and one woodwork teacher (alder). Hence, no correlation between exposure and sensitization to wood dust was found, and the results do not support the assumption that the complaints related to exposure to dusts from the examined Scandinavian woods are IgE mediated.
引用
收藏
页码:559 / 562
页数:4
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