THE DYNAMICS OF AGING AND MORTALITY IN THE UNITED-STATES, 1900-1988

被引：19

作者：

RIGGS, JE

机构：

[1] W VIRGINIA UNIV,MED CTR,SCH MED,DEPT NEUROL,MORGANTOWN,WV 26506

[2] W VIRGINIA UNIV,MED CTR,SCH MED,DEPT MED,MORGANTOWN,WV 26506

[3] W VIRGINIA UNIV,MED CTR,SCH MED,DEPT COMMUNITY MED,MORGANTOWN,WV 26506

来源：

MECHANISMS OF AGEING AND DEVELOPMENT | 1992年 / 66卷 / 01期

关键词：

AGING; MORTALITY; EPIDEMIOLOGY; GOMPERTZIAN ANALYSIS;

D O I：

10.1016/0047-6374(92)90072-L

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The Strehler-Mildvan modification of the Gompertz relationship between aging and mortality provides a dynamic theoretical model for identifying and separating genetic, environmental and competitive influences upon age-related mortality. The initial method of longitudinal Gompertzian analysis, which utilized linear regression, tended to underestimate both genetic and environmental influences upon age-related mortality. A modified method of longitudinal Gompertzian analysis has been applied to mortality due to stomach cancer, cervical cancer and emphysema. This modified method of longitudinal Gompertzian analysis suggests that the genetic influence upon age-related mortality is essentially the same for both men and women. Moreover, application of this modified method suggests that environmental influences upon age-related mortality in the United States have been declining for the past 20 years for men and for the past 45 years for women.

引用

页码：45 / 57

页数：13

共 19 条

[1]

Gompertz B., 1825, PHILOS T R SOC LOND, V115, P513, DOI DOI 10.1098/RSTL.1825.0026

[2] ON THE THERMODYNAMICAL AND BIOLOGICAL INTERPRETATION OF THE GOMPERTZIAN MORTALITY-RATE DISTRIBUTION [J].