ON THE EVOLUTIONARY HISTORY OF THE CIRCUMSPOROZOITE PROTEIN IN PLASMODIA

被引：13

作者：

DIGIOVANNI, L ^{[1
]}

COCHRANE, AH ^{[1
]}

ENEA, V ^{[1
]}

机构：

[1] NYU,MED CTR,DEPT MED & MOLEC PARASITOL,NEW YORK,NY 10010

来源：

EXPERIMENTAL PARASITOLOGY | 1990年 / 70卷 / 04期

关键词：

D O I：

10.1016/0014-4894(90)90120-2

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

We report the complete nucleotide sequence of the circumsporozoite (CS) gene of Plasmodium brasilianum and present an analysis of its evolutionary profile. Despite the lack of a reliable time scale, the analysis of the number and distribution of fixations among seven taxa provides a first glimpse of the evolutionary history of the CS gene, and suggests that the branching events of this gene are completely unconnected with-and far precede in time-the speciation event of the parasite's vertebrate hosts. © 1990.

引用

页码：373 / 381

页数：9

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