FACILE AND HIGHLY STEREOSELECTIVE ALLYLATION OF ALDEHYDES USING ALLYLTRICHLOROSILANES IN DMF

被引：128

作者：

KOBAYASHI, S

NISHIO, K

机构：

[1] Department of Applied Chemistry, Faculty of Science, Science University of Tokyo (SUT), Shinjuku-ku, Tokyo, 162, Kagurazaka

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(00)79181-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Allyltrichlorosilanes regioselectively react with aldehydes in N,N-dimethylformamide (DMF) without catalyst to afford the corresponding homoallylic alcohols in high yields. Syn and anti homoallylic alcohols are stereoselectively obtained from (Z)- and (E)-crotyltrichlorosilane, respectively, under neutral conditions.

引用

页码：3453 / 3456

页数：4

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