A MILD, SELECTIVE METHOD FOR PREPARATION OF VICINAL FLUORO ETHERS USING F-TEDA-BF4

被引：43

作者：

STAVBER, S ^{[1
]}

SOTLER, T ^{[1
]}

ZUPAN, M ^{[1
]}

机构：

[1] UNIV LJUBLJANA,DEPT CHEM,LJUBLJANA 61000,SLOVENIA

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)79977-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Vicinal alkoxy fluorides are efficiently formed by room temperature reaction of phenyl substituted alkenes with commercially available 1-chloromethyl-4-fluoro-1,4-diazobicyclo[2.2.2]octane bis tetrafluoroborate (Selectfluor(TM) F-Teda BF4) in CH3CN in the presence of various alcohols. The reaction follows Markovnikov-type regioselectivity, while stereoselectivity in the case of phenyl substituted benzocyclenes strongly depends on the ring size and the structure of the alcohol.

引用

页码：1105 / 1108

页数：4

共 24 条

[1]

Banks R.E., 1992, US Patent, Patent No. [5086178, 5,086,178]

[2] 1-ALKYL-4-FLUORO-1,4-DIAZONIABICYCLO[2.2.2]OCTANE SALTS - A NOVEL FAMILY OF ELECTROPHILIC FLUORINATING AGENTS [J].