Neutron high-resolution spectroscopic studies of biomolecular dynamics have been pursued actively in the last decade due to the recognised role of the microscopic dynamics in determining the functional properties of many biomolecular assemblies. As a result of instrumental advances and progress in molecular dynamics simulations it is nowadays possible to describe quantitatively the complex low-frequency motions exhibited by biologically active systems. Some selected examples referring to different biopolymers and biological membranes will be illustrated.