WHAT IS A NEONATAL SEIZURE - PROBLEMS IN DEFINITION AND QUANTIFICATION FOR INVESTIGATIVE AND CLINICAL PURPOSES

被引:74
作者
SHEWMON, DA
机构
[1] Department of Pediatrics, Division of Neurology, University of California at Los Angeles School of Medicine, Los Angeles, CA
关键词
Definition; Neonatal seizure; Newborn; Seizure; Semiotics;
D O I
10.1097/00004691-199007000-00003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Despite the clinical and basic scientific importance of neonatal seizures, a standard operational definition of them is lacking. Virtually all quantitative studies of phenomenology, prevalence, treatment efficacy, and prognosis have been undermined by inadequate or inconsistent criteria for the object of investigation. This is not so much a fault of the studies, however, as a consequence of the very nature of neonatal seizures themselves, which seem to defy universally applicable definitions and criteria for quantification. The main obstacles to formulating such definitions are reviewed, and directions for further research are suggested. © 1990 American Electroencephalographic Society.
引用
收藏
页码:315 / 368
页数:54
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共 162 条
[41]  
Engel J., Wilson C.L., Evidence for enhanced synaptic inhibition in human epilepsy, Neurotransmitters, seizures and epilepsy. III, pp. 1-10, (1986)
[42]  
Engel R.C.H., Abnormal electroencephalograms in the neonatal period, (1975)
[43]  
Erkulvrawatr S., Occurrence, evolution and prognosis of periodic lateralized epileptiform discharges in EEG, Clin Electroencephalogr, 8, pp. 89-99, (1977)
[44]  
Estivill E., Sanmarti F., Fernandez-Alvarez E., Morphologie lectroencphalographique des crises du nouveau-n, Rev EEG Neurophysiolterme, 13, pp. 145-152, (1983)
[45]  
Estivill E., Sanmarti F.X., Schossland E., Pineda M., Considrations sur les encphalopathies pileptiques nonatales propos d'une observation personnelle, Rev EEG Neurophysiol, 14, pp. 197-202, (1984)
[46]  
Eyre J.A., Oozeer R.C., Wilkinson A.R., Diagnosis of neonatal seizure by continuous recording and rapid analysis of the electroencephalogram, Arch Dis Child, 58, pp. 785-790, (1983)
[47]  
Fenichel G.M., Difficulty in clinical identification of neonatal seizures: An EEG monitor study, Yale J Biol Med, 60, pp. 139-142, (1987)
[48]  
Ferguson J.H., Levinsohn M.W., Derakshan I., Brainstem seizures in hydranencephaly, Neurology, 24, pp. 1152-1157, (1974)
[49]  
Francis P.L., Self P.A., McCaffree M.A., Behavioral assessment of a hydranencephalic neonate, Child Dev, 55, pp. 262-266, (1984)
[50]  
Fujikawa D.G., Dwyer B.E., Lake R.R., Wasterlain C.G., Local cerebral glucose utilization during status epilepticus in newborn primates, Am J Physiol, 256, 6, pp. C1160-C1167, (1989)