MOLECULAR EPIDEMIOLOGY OF HIV-1 IN MADRID

被引：19

作者：

ROJAS, JM

DOPAZO, J

NAJERA, I

SANCHEZPALOMINO, S

OLIVARES, I

MARTIN, MJ

BERNAL, A

SAIZ, AG

NAJERA, R

LOPEZGALINDEZ, C

机构：

[1] INST SALUD CARLOS III, CTR BIOL CELULAR & RETROVIRUS, E-28220 MADRID, SPAIN

[2] INIA, CTR INVEST SANIDAD ANIM, E-28130 VALDEOLMOS, SPAIN

来源：

VIRUS RESEARCH | 1994年 / 31卷 / 03期

关键词：

HIV-1; HETEROGENEITY; MOLECULAR EPIDEMIOLOGY; PHYLOGENETIC TREE; DISTRIBUTION OF VARIANTS; RISK PRACTICES;

D O I：

10.1016/0168-1702(94)90026-4

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Thirteen HIV-1 isolates from patients of different risk groups in Madrid (Spain) have been analyzed at the genetic level. Two distinct lineages of subtype B have been detected among the HIV-1 circulating in this area: one was related to SF-2/RF strains, whereas the other consists of a more heterogeneous group related to reference strain III-B. Variants of each lineage appeared to circulate preferentially within a risk group: III-B among intravenous drug users, and RF/SF-2 among male homosexuals.

引用

页码：331 / 342

页数：12

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