INFLUENCE OF ELECTROMAGNETIC-FIELDS ON MORPHOLOGY AND MITOCHONDRIAL ACTIVITY OF BREAST-CANCER CELL LINE-MCF7

被引：8

作者：

JOHANN, S

LEDERER, T

MIKOREY, S

KRAUS, W

BLUMEL, G

机构：

[1] Institut für Experimentelle Chirurgie der TU München, 8000 München 80

来源：

BIOELECTROCHEMISTRY AND BIOENERGETICS | 1993年 / 30卷 / 1-3期

关键词：

D O I：

10.1016/0302-4598(93)80070-B

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cells of the breast cancer cell line MCF7 were exposed to electromagnetic fields (EMF). A sinusoidal signal (12 h/day) was generated by a function generator with a frequency of 20 Hz and a maximum magnetic induction of 5.3 mT. After 6 days EMF subjected cells showed a significant increase in mitochondrial activity as shown by MTT-assay. At the same time EMF exposed cells investigated by scanning electron microscopy indicated intensified membrane ruffling and pronounced microvilli development compared with control cells.

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页码：127 / 132

页数：6

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