STRUCTURES OF NEW PSEUDO-PEPTIDE ANTIBIOTICS, SPERABILLINS

被引：11

作者：

HIDA, T ^{[1
]}

TSUBOTANI, S ^{[1
]}

FUNABASHI, Y ^{[1
]}

ONO, H ^{[1
]}

HARADA, S ^{[1
]}

机构：

[1] TAKEDA CHEM IND LTD, DIV PHARMACEUT RES, YODOGAWA KU, OSAKA 532, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1993年 / 66卷 / 03期

关键词：

D O I：

10.1246/bcsj.66.863

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Sperabillins, novel antibiotics, were isolated from the culture filtrate of Pseudomonas fluorescens YK-437. The structure of sperabillin A was elucidated to be 3-[[(3R,5R)-3-amino-6-[(2E,4Z)-2,4-hexadienoylamino]-5-hydroxyhexanoyl]amino]propanamidine dihydrochloride. Sperabillin B has a methyl substituent at the C-6 position of sperabillin A. Sperabillin C and D are (2E,4E)-isomers of the 2,4-hexadienoyl moiety of sperabillin A and B, respectively.

引用

页码：863 / 869

页数：7

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