DIFFERENT BEHAVIORS OF BENZNIDAZOLE AS FREE-RADICAL GENERATOR WITH MAMMALIAN AND TRYPANOSOMA-CRUZI MICROSOMAL PREPARATIONS

被引：108

作者：

MORENO, SNJ

DOCAMPO, R

MASON, RP

LEON, W

STOPPANI, AOM

机构：

[1] UNIV BUENOS AIRES, FAC MED,INST QUIM BIOL, CONSEJO NACL INVEST CIENT & TECN, CTR INVEST BIOENERGET, RA-1121 BUENOS AIRES, ARGENTINA

[2] NIEHS, RES TRIANGLE PK, NC 27709 USA

[3] UNIV FED RIO DE JANEIRO, INST MICROBIOL, RIO DE JANEIRO, RJ, BRAZIL

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1982年 / 218卷 / 02期

关键词：

D O I：

10.1016/0003-9861(82)90383-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：585 / 591

页数：7

共 31 条

[1] MAMMALIAN-CELL TOXICITY OF NITRO-COMPOUNDS - DEPENDENCE UPON REDUCTION POTENTIAL [J].

ADAMS, GE ;

CLARKE, ED ;

JACOBS, RS ;

STRATFORD, IJ ;

WALLACE, RG ;

WARDMAN, P ;

WATTS, ME .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1976, 72 (03) :824-829

[2] HEMOPROTEINS IN TRYPANOSOMA-CRUZI WITH EMPHASIS ON MICROSOMAL PIGMENTS [J].

AGOSIN, M ;

NAQUIRA, C ;

CAPDEVILA, J ;

PAULIN, J .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY, 1976, 7 (11) :585-&

[3] INSITU RADIOLYSIS ELECTRON-SPIN RESONANCE STUDY OF RADICAL-ANIONS OF SUBSTITUTED NITROIMIDAZOLES AND NITROAROMATIC COMPOUNDS [J].

AYSCOUGH, PB ;

ELLIOT, AJ ;

SALMON, GA .

JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS I, 1978, 74 :511-518

[4] USE OF ACETYLATED FERRICYTOCHROME-C FOR DETECTION OF SUPEROXIDE RADICALS PRODUCED IN BIOLOGICAL-MEMBRANES [J].

AZZI, A ;

MONTECUCCO, C ;

RICHTER, C .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 65 (02) :597-603

[5] ANAEROBIC REDUCTION OF NITROIMIDAZOLES BY REDUCED FLAVIN MONO-NUCLEOTIDE AND BY XANTHINE-OXIDASE [J].

CLARKE, ED ;

WARDMAN, P ;

GOULDING, KH .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (19) :2684-2687

[6]

DEBOISO JF, 1971, P SOC EXP BIOL MED, V136, P215, DOI 10.3181/00379727-136-35230

[7]

Docampo R., 1980, The host-invader interplay. (Proc. 3rd Internat. Symp. on the biochemistry of parasites and host-parasite relationships, Beerse, Belgium, 30 June to 3 July 1980.), P677

[8] GENERATION OF SUPEROXIDE ANION AND HYDROGEN-PEROXIDE INDUCED BY NIFURTIMOX IN TRYPANOSOMA-CRUZI [J].

DOCAMPO, R ;

STOPPANI, AOM .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1979, 197 (01) :317-321

[9] MECHANISM OF NIFURTIMOX TOXICITY IN DIFFERENT FORMS OF TRYPANOSOMA-CRUZI [J].

DOCAMPO, R ;

MORENO, SNJ ;

STOPPANI, AOM ;

LEON, W ;

CRUZ, FS ;

VILLALTA, F ;

MUNIZ, RFA .

BIOCHEMICAL PHARMACOLOGY, 1981, 30 (14) :1947-1951

[10] LIPID PEROXIDATION AND GENERATION OF FREE-RADICALS, SUPEROXIDE ANION, AND HYDROGEN-PEROXIDE IN BETA-LAPACHONE-TREATED TRYPANOSOMA-CRUZI EPIMASTIGOTES [J].

DOCAMPO, R ;

CRUZ, FS ;

BOVERIS, A ;

MUNIZ, RPA ;

ESQUIVEL, DMS .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1978, 186 (02) :292-297

← 1 2 3 4 →