INDICATION OF A MODIFIED EMP PATHWAY FOR FRUCTOSE BREAKDOWN IN A HALOPHILIC ARCHAEBACTERIUM

被引：20

作者：

ALTEKAR, W

RANGASWAMY, V

机构：

[1] Biochemistry Division, Bhabha Atomic Research Centre, Bombay, Trombay

来源：

FEMS MICROBIOLOGY LETTERS | 1990年 / 69卷 / 1-2期

关键词：

1-Phosphofructokinase; Fructose metabolism; Halophilic archaebacteria; Ketohexokinase; Modified EMP pathway;

D O I：

10.1016/0378-1097(90)90428-S

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The breakdown of fructose in Haloarcula (Halobacterium) vallismortis probably takes place via a novel modification of Embden Meyerhof-Parnas (EMP) pathway. Phosphorylation of fructose to yield frutose 1-phosphate as the product appears to be the initial step in fructose utilization. The noteworthy feature is that fructose 1-phosphate formation occurs by an ATP-dependent fructose 1-phosphotransferase (ketohexokinase) rather than by the phosphoenolpyruvate-dependent fructose phosphotransferase system, commonly found in eubacteria. Ketohexokinase activity has so far been known to occur only in eukaryotes. Fructose 1-phosphate was converted into fructose 1,6-biphosphate by the action of 1-phosphofructokinase. Ketohexokinase and 1-phosphofructokinase activities have been demonstrated for the first time in any archaebacterium. © 1990.

引用

页码：139 / 143

页数：5

共 21 条

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