INDUCED PHOTOLYSIS OF RABBIT RED-BLOOD-CELLS BY SEVERAL PHOTOSENSITIZERS

被引：18

作者：

JUARRANZ, A

VILLANUEVA, A

DIAZ, V

RODRIGUEZBORLADO, L

TRIGUEROS, C

CANETE, M

机构：

[1] Deparmento de Biologia, Facultad de Ciencias, Universidad Autonoma de Madrid

来源：

ANTI-CANCER DRUGS | 1993年 / 4卷 / 04期

关键词：

MEMBRANE; PHOTOHEMOLYSIS; PHOTOSENSITIZERS; SINGLET OXYGEN;

D O I：

10.1097/00001813-199308000-00012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The photolysis of rabbit red blood cells induced by several photosensitizers has been studied. Membrane photohemolysis was found to be dependent on light dose (J/cm2) for hematoporphyrin (HP), methylene blue (MB) and toluidine blue (TB). No significant hemolysis was detected when mesotetra (4N-methylpyridyl) porphine (T4MP(y)P) plus light was used. Sodium azide inhibited, whereas deuterium oxide potentiated membrane lysis with HP, MB and TB. In the case of T4MP(y)P no differences were observed when using sodium azide or deuterium oxide.

引用

页码：501 / 504

页数：4

共 14 条

[1] SOME PREVALENT BIOMOLECULES AS DEFENSES AGAINST SINGLET OXYGEN DAMAGE [J].