SOLID-PHASE SYNTHESIS OF THE FIBRONECTIN GLYCOPEPTIDE V(GAL-BETA-3GALNAC-ALPHA)THPGY, ITS BETA ANALOG, AND THE CORRESPONDING UNGLYCOSYLATED PEPTIDE

被引：20

作者：

LUNING, B ^{[1
]}

NORBERG, T ^{[1
]}

RIVERABAEZA, C ^{[1
]}

TEJBRANT, J ^{[1
]}

机构：

[1] BIOCARB TECHNOL AB,DEPT ORGAN SYNTH,S-22370 LUND,SWEDEN

来源：

GLYCOCONJUGATE JOURNAL | 1991年 / 8卷 / 06期

关键词：

GLYCOPEPTIDE; SYNTHESIS; FIBRONECTIN;

D O I：

10.1007/BF00769846

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The fibronectin fragment VTHPGY and the corresponding glycopeptides V(Ga1-beta-3GalNAc-alpha)THPGY and V(Gal-beta-3GalNAc-beta)THPGY were synthesized by the FMOC/solid phase approach. FMOC derivatives of threonine, carrying O-linked, peracetylated Gal-beta-3GalNAc chains were used for introduction (HOBt-mediated coupling) of the disaccharide moieties.

引用

页码：450 / 455

页数：6