LYMPHOCYTIC MASTOPATHY - AN AUTOIMMUNE-DISEASE OF THE BREAST

被引：97

作者：

SCHWARTZ, IS ^{[1
]}

STRAUCHEN, JA ^{[1
]}

机构：

[1] CUNY MT SINAI SCH MED,DEPT PATHOL,NEW YORK,NY 10029

来源：

AMERICAN JOURNAL OF CLINICAL PATHOLOGY | 1990年 / 93卷 / 06期

关键词：

Autoimmune; Lymphocytic infiltration; Mastitis; Mastopathy;

D O I：

10.1093/ajcp/93.6.725

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Eight cases are reported of an unusual breast lesion consisting of dense intralobular, perilobular, and perivascular lymphocytic infiltrates associated with lobular atrophy and sclerosis. Immunologic studies on paraffin-embedded tissue (seven cases) and frozen tissue (two cases) demonstrated a predominance of B-cells and expression of HLA-DR antigen in involved lobular epithelium. The immunologic features of this lesion are reminiscent of lymphoepithelial lesions of salivary glands and other sites. A possible autoimmune pathogenesis is suggested.

引用

页码：725 / 730

页数：6