ENANTIOMER ENRICHMENT OF OXPRENOLOL THROUGH CELLULOSE TRIS(3,5-DIMETHYLPHENYLCARBAMATE) MEMBRANE

被引：38

作者：

YASHIMA, E

NOGUCHI, J

OKAMOTO, Y

机构：

[1] Department of Applied Chemistry, School of Engineering, Nagoya University, Nagoya, 464-01, Chikusa-ku

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 1994年 / 54卷 / 08期

关键词：

D O I：

10.1002/app.1994.070540811

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Enantioselective enrichment of racemic oxprenolol dissolved in a hexane-2-propanol mixture was achieved with a solid chiral polymer membrane consisting of cellulose tris(3,5-di-methylphenylcarbamate) coated on a Teflon membrane filter. The oxprenolol obtained through the membrane was rich in (S)-isomer up to about 50% ee at initial stage and (R) -enrichment of a source phase (23% ee) was achieved. (C) 1994 John Wiley and Sons, Inc.

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页码：1087 / 1091

页数：5

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