BIOSYNTHESIS OF HETEROSCYPHIC ACID-A IN CELL-CULTURES OF HETEROSCYPHUS-PLANUS - NONEQUIVALENT LABELING OF C-5 UNITS IN DITERPENE BIOSYNTHESIS

被引：18

作者：

NABETA, K

ISHIKAWA, T

KAWAE, T

OKUYAMA, H

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 06期

关键词：

D O I：

10.1039/c39950000681

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Preferential labelling in the farnesyl diphosphate (FPP)-derived portion and a 1,2-migration of the methyl (C19) originating at C-6 of mevalonate in the biosynthesis of heteroscyphic acid A {(12Z)-5,10-trans-cleroda-3,12,14-trien-20-oic acid} incorporating [2-C-13]- and [4,5-C-13(2)]-mevalonates are evident from the C-13-enrichment and the complete C-13-C-13 coupling pattern.

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页码：681 / 682

页数：2

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