A POTENT INHIBITOR OF BETA-N-ACETYLGLUCOSAMINIDASES - 6-ACETAMIDO-6-DEOXYCASTANOSPERMINE

被引：39

作者：

LIU, PS

KANG, MS

SUNKARA, PS

机构：

[1] Merrell Dow Research Institute, Cincinnati, OH 45215

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)74866-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile synthesis of 6-acetamido-6-deoxycastanospermine (4) is described. The target compound inhibits mammalian beta-N-acetylglucosaminidases at or below 1-mu-M.

引用

页码：719 / 720

页数：2

共 6 条

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[5] SYNTHESIS OF POTENT ANTI-HIV AGENTS - ESTERS OF CASTANOSPERMINE
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[6] LO CH, 1978, J MED, V9, P313

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