ASYMMETRIC HECK REACTION OF ALKENYL IODIDES IN THE PRESENCE OF SLIVER SALTS - CATALYTIC ASYMMETRIC-SYNTHESIS OF DECALIN AND FUNCTIONALIZED INDOLIZIDINE DERIVATIVES

被引：86

作者：

SATO, Y

NUKUI, S

SODEOKA, M

SHIBASAKI, M

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO,TOKYO 113,JAPAN

[2] HOKKAIDO UNIV,FAC PHARMACEUT SCI,KITA KU,SAPPORO 060,HOKKAIDO,JAPAN

来源：

TETRAHEDRON | 1994年 / 50卷 / 02期

关键词：

D O I：

10.1016/S0040-4020(01)80761-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Decalin derivatives 3 (up to 80% ee) and indolizidine derivative 6 (up to 86% ee) have been synthesized by an asymmetric Heck reaction starling with prochiral alkenyl iodides 1 and 4, respectively. The important role of silver salts in the asymmetric Heck reaction is discussed, and the conversion of 6 to delta-coniceine (24) is also described.

引用

页码：371 / 382

页数：12

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