LYSOSOMOTROPIC AGENTS .4. CARBOBENZOXYGLYCYLPHENYLALANYL, A NEW PROTEASE-SENSITIVE MASKING GROUP FOR INTRODUCTION INTO CELLS

被引：25

作者：

FIRESTONE, RA

PISANO, JM

BAILEY, PJ

STURM, A

BONNEY, RJ

WIGHTMAN, P

DEVLIN, R

LIN, CS

KELLER, DL

TWAY, PC

机构：

[1] MERCK SHARP & DOHME,RES LABS,DEPT ANALYT RES,W POINT,PA 19486

[2] MERCK INST THERAPEUT RES,DEPT IMMUNOL,RAHWAY,NJ 07065

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 05期

关键词：

D O I：

10.1021/jm00347a012

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：539 / 544

页数：6

共 45 条

[31] AMINO-ACID AND DIPEPTIDE DERIVATIVES OF DAUNORUBICIN .1. SYNTHESIS, PHYSICOCHEMICAL PROPERTIES, AND LYSOSOMAL DIGESTION [J].

MASQUELIER, M ;

BAURAIN, R ;

TROUET, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (11) :1166-1170

[32]

MCDONALD JK, 1969, J BIOL CHEM, V244, P2693

[33] FLUORESCENCE PROBE MEASUREMENT OF INTRALYSOSOMAL PH IN LIVING CELLS AND PERTURBATION OF PH BY VARIOUS AGENTS [J].

OHKUMA, S ;

POOLE, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (07) :3327-3331

[34]

OHNUMA T, 1975, CANCER RES, V35, P1767

[35] LYSOSOMOTROPIC AGENTS .3. SYNTHESIS OF N-RETINYL MORPHOLINE [J].

PISANO, JM ;

FIRESTONE, RA .

SYNTHETIC COMMUNICATIONS, 1981, 11 (05) :375-378

[36] EFFECTIVE ANTITUMOUR CONJUGATES OF ALKYLATING DRUG AND ANTIBODY USING DEXTRAN AS INTERMEDIATE CARRIER [J].

ROWLAND, GF .

EUROPEAN JOURNAL OF CANCER, 1977, 13 (06) :593-596

[37] PIGGY-BACK PHAGOCYTOSIS [J].

SBARRA, AJ ;

SHIRLEY, W ;

BARDAWIL, WA .

NATURE, 1962, 194 (4825) :255-&

[38]

SEGLEN PO, 1980, MOL PHARMACOL, V18, P468

[39] INHIBITION OF THE LYSOSOMAL PATHWAY OF PROTEIN-DEGRADATION IN ISOLATED RAT HEPATOCYTES BY AMMONIA, METHYLAMINE, CHLOROQUINE AND LEUPEPTIN [J].

SEGLEN, PO ;

GRINDE, B ;

SOLHEIM, AE .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1979, 95 (02) :215-225

[40]

SORACE RA, 1979, CANCER TREAT REP, V63, P43

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