EXPRESSION OF MESSENGER-RNA FOR THE N-METHYL-D-ASPARTATE (NMDAR1) RECEPTOR BY THE ENTERIC NEURONS OF THE RAT

被引：49

作者：

BURNS, GA

STEPHENS, KE

BENSON, JA

机构：

[1] Department of Veterinary Comparative Anatomy Pharmacology and Physiology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6520

来源：

NEUROSCIENCE LETTERS | 1994年 / 170卷 / 01期

关键词：

RECEPTOR; NMDA; GLUTAMATE; ENTERIC GANGLION; IN SITU HYBRIDIZATION; RAT;

D O I：

10.1016/0304-3940(94)90245-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this study, in situ hybridization techniques were employed to map the distribution of enteric neurons which express mRNA for the glutamate N-methyl-D-aspartate receptor 1 (NMDAR1). We hybridized tissue sections from the stomach, duodenum, ileum and descending colon of adult rats with a 1.43-kB riboprobe cleaved from a clone of the NMDA receptor. Enteric neurons expressing the mRNA were found in both myenteric and submucosal ganglia at each of the sampling sites. Possible functions of NMDA receptors on enteric neurons are discussed.

引用

页码：87 / 90

页数：4

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