URINARY STYRENE IN THE BIOLOGICAL MONITORING OF STYRENE EXPOSURE

被引：20

作者：

GOBBA, F

GALASSI, C

GHITTORI, S

IMBRIANI, M

PUGLIESE, F

CAVALLERI, A

机构：

[1] MED CTR PAVIA,CLIN LAVORO FDN,PAVIA,ITALY

[2] UNIV PAVIA,DEPT PREVENT OCCUPAT & COMMUNITY MED,I-27100 PAVIA,ITALY

[3] OCCUPAT HLTH SERV,LOCAL HLTH UNIT 2,PIACENZA,ITALY

[4] UNIV PAVIA,PREVENT MED WORKERS SECT,I-27100 PAVIA,ITALY

来源：

SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH | 1993年 / 19卷 / 03期

关键词：

BIOLOGICAL EQUIVALENT EXPOSURE LIMIT; BIOLOGICAL EXPOSURE INDEX; GLASS-REINFORCED PLASTICS; STYRENE METABOLITES;

D O I：

10.5271/sjweh.1484

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The urinary excretion of styrene represents a promising indicator of exposure to this solvent. Nevertheless extensive research under field conditions is scant. In this investigation 214 styrene-exposed workers from 10 fiberglass-reinforced plastics factories were studied. Environmental monitoring was performed by personal passive sampling. Blood styrene and the urinary excretion of styrene and its main metabolites, mandelic acid (MA) and phenylglyoxylic acid (PGA), were measured. The correlation coefficient between the time-weighted average of environmental styrene and the mean urinary excretion of styrene was 0.88 (0.91 after logarithmic transformation), compared with the 0.82 and 0.78 of the end-of-shift MA and PGA values, respectively. A high correlation (0.86) was also found between styrene in the blood and urine. The results, obtained under field conditions with a large group of exposed workers, confirm the usefulness of the urinary excretion of styrene as an exposure index for the biological monitoring of styrene exposure.

引用

页码：175 / 182

页数：8