A FACILE ENZYME ASSISTED ROUTE TO (R)-T-BUTYLOXIRANE AND (S)-T-BUTYLOXIRANE AND RELATED BETA-AMINO ALCOHOLS - CATALYSTS FOR THE ENANTIOSELECTIVE ADDITION OF DIALKYLZINC REAGENTS TO ALDEHYDES

被引：10

作者：

CHADHA, A ^{[1
]}

GOERGENS, U ^{[1
]}

SCHNEIDER, MP ^{[1
]}

机构：

[1] BERG UNIV GESAMTHSCH WUPPERTAL,FB 9,W-5600 WUPPERTAL 1,GERMANY

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 07期

关键词：

D O I：

10.1016/S0957-4166(00)80338-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(R) and (S)-t-butyloxirane [(R)- and (S)-3] have been prepared in high enantiomeric purity from racemic t-butyloxirane (+/-)-3 by an enzymatic route. (S)-3 has been used for the preparation of the chiral beta-amino alcohols (R)- and (S)-1,2, which are catalysts for the enantioselective addition of dialkylzinc reagents to aldehydes.

引用

页码：1449 / 1450

页数：2

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