INHIBITION OF THE REVERSE-TRANSCRIPTASE OF HIV-1 BY 3'-AZIDOTHYMIDINE TRIPHOSPHATE AND 3'-AZIDO-OLIGOTHYMIDYLATE

被引：7

作者：

HEIDENREICH, O ^{[1
]}

ECKSTEIN, F ^{[1
]}

机构：

[1] MAX PLANCK INST EXPTL MED,HERMANN REIN STR 3,W-3400 GOTTINGEN,GERMANY

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期

关键词：

D O I：

10.1080/07328319108046519

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The inhibition of HIV-1 reverse transcriptase by 3'-azidothymidine triphosphate (N3-dTTP) and 3'-azidooligothymidylate (N3-(dT)16) was investigated by kinetic analysis. The inhibition patterns suggest for both compounds a dead-end inhibition mode.

引用

页码：535 / 536

页数：2

共 5 条

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