REACTION OF NITRILES UNDER ACIDIC CONDITIONS .6. SYNTHESIS OF CONDENSED 4-CHLOROPYRIMIDINES AND 4-AMINOPYRIMIDINES FROM ORTHO-AMINONITRILES

被引：33

作者：

SHISHOO, CJ

DEVANI, MB

BHADTI, VS

JAIN, KS

ANANTHAN, S

机构：

[1] Department of Pharmaceutical Chemistry, L. M. College of Pharmacy, Ahmedabad

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 02期

关键词：

D O I：

10.1002/jhet.5570270201

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensation of a nitrile with benzene, furan and thiophene ortho‐aminonitriles in the presence of dry hydrogen chloride yields condensed 4‐chloropyrimidines, condensed 4‐aminopyrimidines or a mixture of the two condensed pyrimidines in varying proportions depending upon the nature of the nitrile and the substrate, ortho‐aminonitrile. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：119 / 126

页数：8

共 22 条

[1]

BHADTI VS, 1985, THESIS GUJARAT U

[2]

BREUER H, 1976, TETRAHEDRON LETT, P1935

[3] FORMATION OF TETRAZOLES BY CONDENSATION OF ORGANIC AZIDES WITH NITRILES [J].