CRYSTALLIZATION OF BOVINE PANCREATIC-POLYPEPTIDE IN THE PRESENCE OF CRYSTALLINE DIGLYCIDYL ETHER OF BISPHENOL-A (ARALDITE) - EPITAXY OR COVALENT NUCLEATION
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作者:
WOOD, SP
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机构:Laboratory of Molecular Biology, Department of Crystallography, Birkbeck College, London, WC1E 7HX, Malet Street
WOOD, SP
JANES, RW
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机构:Laboratory of Molecular Biology, Department of Crystallography, Birkbeck College, London, WC1E 7HX, Malet Street
JANES, RW
SWEENEY, E
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机构:Laboratory of Molecular Biology, Department of Crystallography, Birkbeck College, London, WC1E 7HX, Malet Street
SWEENEY, E
PALMER, RA
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机构:Laboratory of Molecular Biology, Department of Crystallography, Birkbeck College, London, WC1E 7HX, Malet Street
PALMER, RA
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[1] Laboratory of Molecular Biology, Department of Crystallography, Birkbeck College, London, WC1E 7HX, Malet Street
Bovine pancreatic polypeptide (bPP), a 36 residue peptide hormone with a stable folded structure in solution has been crystallized from aqueous solution in the presence of seed crystals derived from an ageing sample of commercial epoxy resin. X-ray analysis established these to be crystals of diglycidyl ether of bisphenol A (DGEBA). The possibility of epitaxial or covalent nucleation is discussed.