3' NONCODING REGION OF BETA-GLOBIN MESSENGER-RNA IS NOT ESSENTIAL FOR INVITRO TRANSLATION

被引：41

作者：

KRONENBERG, HM

ROBERTS, BE

EFSTRATIADIS, A

机构：

[1] MIT, DEPT BIOL, CAMBRIDGE, MA 02139 USA

[2] BRANDEIS UNIV, DEPT BIOL, WALTHAM, MA 02154 USA

[3] HARVARD UNIV, SCH MED, DEPT BIOL CHEM, BOSTON, MA 02115 USA

来源：

NUCLEIC ACIDS RESEARCH | 1979年 / 6卷 / 01期

关键词：

D O I：

10.1093/nar/6.1.153

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rabbit β-globin DNA sequence, excised from plasmid pβGl, directs in vitro synthesis of β-globin in a transcription-translation cell-free system, even after specific elimination of the entire 3′-noncoding region. A DNA restriction fragment carrying this 3′ non-coding region and hybridized to globin mRNA cannot arrest the cell-free translation of β-globin mRNA. © 1979 Information Retrieval Limited.

引用

页码：153 / 166

页数：14

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