THROMBOELASTOGRAPHY AFTER ASPIRIN INGESTION IN PREGNANT AND NONPREGNANT SUBJECTS

被引:46
作者
ORLIKOWSKI, CEP
PAYNE, AJ
MOODLEY, J
ROCKE, DA
机构
[1] UNIV NATAL,FAC MED,DEPT ANAESTHESIA,POB 17039,CONGELLA 4013,SOUTH AFRICA
[2] UNIV NATAL,FAC MED,DEPT OBSTET & GYNAECOL,CONGELLA 4013,SOUTH AFRICA
关键词
BLOOD; COAGULATION; PREGNANCY; ASPIRIN THERAPY; MEASUREMENT TECHNIQUES; THROMBOELASTOGRAPHY;
D O I
10.1093/bja/69.2.159
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The thrombelastograph (TEG) and bleeding time were performed before and 6h after a single oral dose of aspirin 600 mg in a group of eight healthy volunteers and 12 pregnant patients. Measured TEG variables (r, k, r + k times and maximum amplitude) were unaltered after aspirin although there was a significant prolongation of the bleeding time in both groups. Although the TEG appeared not to detect aspirin-induced changes in platelet function, the TEG measures all phases of coagulation and the unaltered TEG after aspirin suggested a functioning coagulation system.
引用
收藏
页码:159 / 161
页数:3
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