GUILLAIN-BARRE-SYNDROME ASSOCIATED WITH IGM ANTI-G(M1) ANTIBODY FOLLOWING CAMPYLOBACTER-JEJUNI ENTERITIS

被引：9

作者：

SUGITA, K ^{[1
]}

ISHII, M ^{[1
]}

TAKANASHI, J ^{[1
]}

NIIMI, H ^{[1
]}

YUKI, N ^{[1
]}

机构：

[1] TOKYO MED & DENT UNIV,FAC MED,DEPT BIOCHEM,TOKYO,TOKYO,JAPAN

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1994年 / 153卷 / 03期

关键词：

GUILLAIN-BARRE SYNDROME; ANTI-G(M1) ANTIBODY ANTI-G(M2) ANTIBODY; CAMPYLOBACTER JEJUNI; HLA-B35;

D O I：

10.1007/BF01958981

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We report a 4-year-old girl diagnosed as having Guillain-Barre syndrome after infection by Penner serotype 19 of Campylobacter jejuni. The patient had the HLA-B35 antigen. Neurological examination revealed distal-dominant weakness and intact sensation. Serial electrophysiological studies indicated that the predominant process was axonal degeneration involving motor nerves. An enzyme-linked immunosorbent assay revealed the presence of high titres of serum IgM antibodies to gangliosides G(M1) and GM, The IgM auto-antibody titres decreased concurrently with the clinical course of the illness and no switching from IgM to IgG secretion took place.

引用

页码：181 / 183

页数：3

共 26 条

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