MUTAGENICITY OF NITROSAMINES FORMED FROM NITROSATION OF SPERMIDINE

被引：11

作者：

HOTCHKISS, JH ^{[1
]}

SCANLAN, RA ^{[1
]}

LIJINSKY, W ^{[1
]}

ANDREWS, AW ^{[1
]}

机构：

[1] OREGON STATE UNIV,DEPT FOOD SCI & TECHNOL,CORVALLIS,OR 97331

来源：

MUTATION RESEARCH | 1979年 / 68卷 / 03期

关键词：

D O I：

10.1016/0165-1218(79)90149-6

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

5 nitrosamines formed from the nitrosation of spermidine were investigated for mutagenicity using various strains of Salmonella typhimurium in the presence and absence of S9 mix. Using the plate incorporation method, 3-butenyl-(2-propenyl)-N-nitrosamine, 3-hydroxybutyl(2-hydroxypropyl)-N-nitrosamine, 4-hydroxybutyl-(2-hydroxypropyl)-N-nitrosamine, 4 hydroxybutyl-(3-hydroxypropyl)-N-nitrosamine, and in the liquid test 3-hydroxybutyl-(3-hydroxypropyl)-N-nitrosamine were mutagenic in the absence of S9 mix. © 1979.

引用

页码：195 / 199

页数：5

共 14 条

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[13]

TANNENBAUM SR, 1974, JNCI-J NATL CANCER I, V53, P79

[14] MUTAGENICITY OF HETEROCYCLIC N-NITROSAMINES FOR SALMONELLA-TYPHIMURIUM [J].

ZEIGER, E ;

SHELDON, AT .

MUTATION RESEARCH, 1978, 57 (01) :1-10

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