INCREASED PLASMA ACTIVITIES OF N-ACETYL-BETA-D-GLUCOSAMINIDASE ISOENZYMES IN HUMAN DIABETES-MELLITUS

被引：25

作者：

POON, PYW

DORNAN, TL

ELLIS, RB

TURNER, RC

机构：

[1] UNIV OXFORD,RADCLIFFE INFIRM,OXFORD OX2 6HE,ENGLAND

[2] INST CHILD HLTH,LONDON WC1N 1EH,ENGLAND

来源：

CLINICAL ENDOCRINOLOGY | 1979年 / 11卷 / 06期

关键词：

D O I：

10.1111/j.1365-2265.1979.tb03117.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma N‐acetyl‐β‐D‐glucosaminidase activities are raised in maturity‐onset insulin‐dependent diabetic patients. Continuous gradient DEAE‐cellulose column chromatography and assay of heat‐stable enzyme activity both show that the activities of all isoenzymes are equally increased rather than a previously described increase of specific isoenzymes. Plasma enzyme activities are similarly increased in patients with and without diabetic retinopathy, and correlate with simultaneous plasma glucose concentrations. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：625 / 630

页数：6

共 9 条

[1] SERUM N-ACETYL-BETA-GLUCOSAMINIDASE ACTIVITY IN DIABETIC PATIENTS [J].