PATTERN OF INTERLEUKINS IN MINIMAL-CHANGE NEPHROTIC SYNDROME OF CHILDHOOD

被引：34

作者：

SAXENA, S ^{[1
]}

MITTAL, A ^{[1
]}

ANDAL, A ^{[1
]}

机构：

[1] SAFDARJANG HOSP, DEPT PAEDIAT NEPHROL, NEW DELHI 110016, INDIA

来源：

NEPHRON | 1993年 / 65卷 / 01期

关键词：

INTERLEUKINS; LYMPHOKINES; MINIMAL-CHANGE NEPHROTIC SYNDROME;

D O I：

10.1159/000187441

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Assays of interleukin-1 (IL-1) and IL-2 were done in supernatants from phytohaemagglutinin-activated lymphocyte cultures from 10 children suffering from minimal-change nephrotic syndrome (MCNS) to assess their role in the aetiopathogenesis of this disorder. Increased levels of IL-1 and IL-2 had been found in supernatants from patients having MCNS compared with controls, suggesting a significant role of these cytokines in the immunopathogenesis of proteinuria in this syndrome.

引用

页码：56 / 61

页数：6

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