TOXAPHENE, A COMPLEX MIXTURE OF POLYCHLOROTERPENES AND A MAJOR INSECTICIDE, IS MUTAGENIC

被引：56

作者：

HOOPER, NK ^{[1
]}

AMES, BN ^{[1
]}

SALEH, MA ^{[1
]}

CASIDA, JE ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY,DEPT ENTOMOL SCI,PESTICIDE CHEM & TOXICOL LAB,BERKELEY,CA 94720

来源：

SCIENCE | 1979年 / 205卷 / 4406期

关键词：

D O I：

10.1126/science.377495

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Toxaphene, the most widely used chlorinated insecticide, is mutagenic in the Salmonella test without requiring liver homogenate for activity. This insecticide is a complex mixture (more than 177 polychloroterpenes) with carcinogenic activity in rodents. Some but not all of the mutagenic components are easily separated from the insecticidal ingredients. Copyright © 1979 AAAS.

引用

页码：591 / 593

页数：3