CHEMICAL MODIFICATION OF PARAHERQUAMIDE .3. VINYL ETHER MODIFIED ANALOGS

被引：10

作者：

BLIZZARD, TA

MARGIATTO, G

MROZIK, H

SCHAEFFER, JM

FISHER, MH

机构：

[1] Merck Sharp and Dohme Research Laboratories R50G-231, Rahway, NJ 07065

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(00)74347-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several analogs of paraherquamide, a novel anti-parasitic agent, are described. One series of analogs (4a-d) is the result of net addition of an alcohol to the vinyl ether while a second series (5-8) is derived via ozonolysis. Biological activity of the analogs is discussed briefly.

引用

页码：2437 / 2440

页数：4

共 13 条

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