CIMETIDINE IN THE PREVENTION OF THE PULMONARY ACID ASPIRATION (MENDELSONS) SYNDROME

被引:36
作者
DOBB, G [1 ]
JORDAN, MJ [1 ]
WILLIAMS, JG [1 ]
机构
[1] ST THOMAS HOSP & MED SCH,DEPT ANAESTHESIA,LONDON SE1 7EH,ENGLAND
关键词
D O I
10.1093/bja/51.10.967
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Cimetidine 200 mg was given i.v. 1 h before induction of anaesthesia to 20 patients about to undergo emergency surgery. There was an increase in pH of gastric aspirate in all patients (P < 0.001) and in 80% pH was greater than 2.5 units at the time of induction of anaesthesia. The pH of gastric aspirate continued to increase after induction of anaesthesia and was greater than 4 units in all patients at the time of tracheal extubation and in the early recovery period. © 1979 Macmillan Journals Ltd.
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收藏
页码:967 / 970
页数:4
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