SYNTHESIS OF NEW STEROIDAL 11-BETA-SUBSTITUTED SPIROLACTONES

被引:16
作者
FARAJ, H
CLAIRE, M
RONDOT, A
AUMELAS, A
AUZOU, G
机构
[1] FAC PHARM MONTPELLIER,INSERM,U300,15 AVE CHARLES FLAHAULT,F-34060 MONTPELLIER 1,FRANCE
[2] INSERM,CNRS,UA 264,F-34094 MONTPELLIER,FRANCE
来源
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 11期
关键词
D O I
10.1039/p19900003045
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A stereoselective synthesis of new 3-oxo-11β-(3-alkoxypropyl)-19-nor- 17α-pregna-4,9-diene21,17-carbolactones has been achieved. The purpose of this study was to synthesize new 11βsubstituted spirolactones by a new approach. A variety of NMR techniques were utilized to make complete assignments of this type of steroids in solution.
引用
收藏
页码:3045 / 3048
页数:4
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