DISPLACEMENT OF SUGAR TRIFLATES WITH C-NUCLEOPHILES - D-GLUCOPYRANOSE AND D-RIBOFURANOSE CHAIN EXTENSION AND FUNCTIONALIZATION

被引：27

作者：

SHEN, QR

SLOSS, DG

BERKOWITZ, DB

机构：

[1] Department of Chemistry, University of Nebraska-Lincoln, Lincoln

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 11期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1080/00397919408010152

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of methyl 4-O-benzyl-2,3-di-O-methoxymethyl-6-O-trifluoromethanesulfonyl-alpha-D-glucopyranoside 1 or 3-O-benzyl-1,2-O-isopropylidene-5-O-trifluoromethenesulfonyl-alpha-D-ribofuranoside 2 with a variety of functionalized C-nucleophiles in THF/HMPA leads to the corresponding chain-extended sugars in very good to excellent yields.

引用

收藏

页码：1519 / 1530

页数：12

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