RING-D EXPANSION AND AROMATIZATION IN THE BIOSYNTHESIS OF NIC-1, AN ANTIFEEDANT STEROID FROM NICANDRA-PHYSALOIDES

被引：16

作者：

GILL, HK ^{[1
]}

SMITH, RW ^{[1
]}

WHITING, DA ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 11期

关键词：

D O I：

10.1039/p19900002989

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Isotope administration experiments with Nicandra physaloides plants using [3'-C2H3]- and [3'-14C3]mevalonic acid, analysed by 2H NMR and by degradation, respectively, show that the aromatic ring-D of Nic-1 2 is formed by ring-D expansion in a steroid precursor with oxidative inclusion of the C/D angular methyl.

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收藏

页码：2989 / 2993

页数：5

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