NOVEL AND EFFICIENT SYNTHESIS OF 1-BETA-METHYLCARBAPENEMS UTILIZING CYCLIZATION OF HYPERVALENT IODONIUM YLIDES

被引：27

作者：

KUME, M

KUBOTA, T

ISO, Y

机构：

[1] Shionogi Research Laboratories, Shionogi and Co., Ltd., Fukushima-ku, Osaka

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 44期

关键词：

D O I：

10.1016/0040-4039(95)01703-K

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1 beta-Methylcarbapenems were efficiently synthesized utilizing acid- and rhodium(II)-catalyzed cyclization of iodonium ylide intermediates, which were easily prepared from the corresponding beta-keto ester derivatives.

引用

页码：8043 / 8046

页数：4

共 14 条

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