STEROL MOLECULE - STRUCTURE, BIOSYNTHESIS, AND FUNCTION

被引：199

作者：

BLOCH, K

机构：

来源：

STEROIDS | 1992年 / 57卷 / 08期

关键词：

STEROLS; CHOLESTEROL; BIOLOGIC SYNTHESIS; HISTORY OF CHEMICAL STRUCTURE;

D O I：

10.1016/0039-128X(92)90081-J

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review briefly summarizes key researches on the structure of the sterol molecule from its very beginnings to the definitive elucidation in 1932. Cholesterol biosynthesis treated in somewhat greater detail covers the period from the 1930s to the 1960s. As a historic contribution, it presents researches previously published in numerous books, reviews, and original papers. The selection of topics, dictated by limits of time and space, is necessarily arbitrary and a personal choice. Readers of this journal will be familiar with the relevant chemical structures. Structural formulas are therefore omitted.

引用

页码：378 / 383

页数：6

共 44 条

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BLOCH, K
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1982, 7 (09) : 334 - 336
[7] UBER DIE HERKUNFT DES KOHLENSTOFF-ATOMS-7 IN CHOLESTERIN - EIN BEITRAG ZUR KENNTNIS DER BIOSYNTHESE DER STEROIDE
BLOCH, K
[J]. HELVETICA CHIMICA ACTA, 1953, 36 (06) : 1611 - 1614
[8] CASTELLS J, 1956, CHEM IND, V14, P248
[9] The biological significance of the unsaponifiable matter of oils. I. Experiments with the unsaturated hydrocarbon, squalene (spinacene).
Channon, HJ
[J]. BIOCHEMICAL JOURNAL, 1926, 20 (02) : 400 - 408
[10] PHOSPHORYLATED INTERMEDIATES IN THE SYNTHESIS OF SQUALENE
CHAYKIN, S
LAW, J
PHILLIPS, AH
TCHEN, TT
BLOCH, K
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1958, 44 (10) : 998 - 1004

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