COLONIC BACTERIAL PROTEASES TO IGA1 AND SIGA IN PATIENTS WITH ULCERATIVE-COLITIS

被引：6

作者：

BARR, GD

HUDSON, MJ

PRIDDLE, JD

JEWELL, DP

机构：

[1] RADCLIFFE INFIRM, DEPT GASTROENTEROL, OXFORD OX2 6HE, ENGLAND

[2] CTR APPL MICROBIOL & RES, PUBL HLTH LAB SERV, SALISBURY, WILTS, ENGLAND

来源：

GUT | 1987年 / 28卷 / 02期

关键词：

D O I：

10.1136/gut.28.2.186

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The colonic faecal and mucosal associated bacterial populations of five patients with ulcerative colitis and four control patients were studied in detail to assess their ability to produce IgA1-proteases. A total of 330 bacterial strains were isolated from the patients with ulcerative colitis and IgA1-protease activity was unable to be reliably shown in any. It is therefore unlikely that such enzyme production by colonic bacteria plays a significant role in the pathogenesis of ulcerative colitis.

引用

页码：186 / 189

页数：4

共 21 条

[11] ECOLOGY AND NATURE OF IMMUNOGLOBULIN-A1 PROTEASE-PRODUCING STREPTOCOCCI IN THE HUMAN ORAL CAVITY AND PHARYNX [J].