CHROMOSOME REPLICATION AND SYNTHESIS OF NON-HISTONE PROTEINS IN GIANT POLYTENE CHROMOSOMES

被引：17

作者：

CAVE, MD

机构：

[1] Max-Planck-Institut für Biologic, Abtcilung BEEEMANN, Tübingen

[2] Department of Anatomy and Cell Biology, University of Pittsburgh

来源：

CHROMOSOMA | 1968年 / 25卷 / 04期

关键词：

D O I：

10.1007/BF02327720

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Synthesis of chromosomal proteins was studied by means of autoradiography in giant polytene chromosomes of Chironomus thummi. Incorporation of tryptophane-H3 into non-histone proteins of the chromosome does not increase during DNA synthesis. Grain count data reveal that chromosomes of cells which are actively replicating DNA do not differ from non-replicating cells in regard to the incorporation of tryptophane-H3 into chromosomal non-histone protein. Chromosomes of cells which are replicating DNA incorporate about 2 times more lysine-H3 than do non-DNA replicating cells. Synthesis of histones accounts for this increase in lysinc-H3 incorporation. © 1968 Springer-Verlag.

引用

页码：392 / +

页数：1