IDENTIFICATION OF COMPLEX T(15,17) IN APL BY FISH

被引：33

作者：

CHEN, Z ^{[1
]}

MORGAN, R ^{[1
]}

STONE, JF ^{[1
]}

SANDBERG, AA ^{[1
]}

机构：

[1] SW BIOMED RES INST & GENETRIX INC, CTR CANC, SCOTTSDALE, AZ 85251 USA

来源：

CANCER GENETICS AND CYTOGENETICS | 1994年 / 72卷 / 01期

关键词：

D O I：

10.1016/0165-4608(94)90114-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Fluorescence in situ hybridization (FISH) provides a sensitive and effective approach in identifying the RAR-alpha/PML fusion event in acute promyelocytic leukemia (APL) with the t(15;17). In the present study we describe the use of this assay for the identification of the RAR-alpha/PML fusion in bone marrow (BM) cells from three APL patients with complex t(15;17) translocations.

引用

页码：73 / 74

页数：2

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