LIBRARY-BASED LEAD COMPOUND DISCOVERY - ANTIOXIDANTS BY AN ANALOGOUS SYNTHESIS DECONVOLUTIVE ASSAY STRATEGY

被引：80

作者：

KURTH, MJ ^{[1
]}

RANDALL, LAA ^{[1
]}

CHEN, CX ^{[1
]}

MELANDER, C ^{[1
]}

MILLER, RB ^{[1
]}

MCALISTER, K ^{[1
]}

REITZ, G ^{[1
]}

KANG, R ^{[1
]}

NAKATSU, T ^{[1
]}

GREEN, C ^{[1
]}

机构：

[1] TAKASAGO INST INTERDISCIPLINARY SCI,WALNUT CREEK,CA 94598

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 20期

关键词：

D O I：

10.1021/jo00099a008

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A two-part demonstration project is reported which utilized analogous synthesis to reliably deliver a 27-analogue Library which was then evaluated for antioxidative efficiency in a resin-free (ferric thiocyanate assay) deconvolutive assay.

引用

页码：5862 / 5864

页数：3

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