DIETHOXY N,N-DIISOPROPYL PHOSPHORAMIDITE AS AN IMPROVED CAPPING REAGENT IN THE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORAMIDITE CHEMISTRY

被引：13

作者：

YU, D ^{[1
]}

TANG, JY ^{[1
]}

IYER, RP ^{[1
]}

AGRAWAL, S ^{[1
]}

机构：

[1] HYBRIDON INC,WORCESTER,MA 01605

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(00)78437-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of diethoxy N, N-diisopropyl phosphoramidite (DDP) as a capping reagent for the synthesis of oligonucleotides, in conjunction with phosphoramidite chemistry, results in overall improvement in quality and yield.

引用

页码：8565 / 8568

页数：4

共 14 条

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