SEMIQUANTITATIVE CALCULATIONS OF CATALYTIC FREE-ENERGIES IN GENETICALLY MODIFIED ENZYMES

被引：89

作者：

HWANG, JK ^{[1
]}

WARSHEL, A ^{[1
]}

机构：

[1] UNIV SO CALIF,DEPT CHEM,LOS ANGELES,CA 90089

来源：

BIOCHEMISTRY | 1987年 / 26卷 / 10期

关键词：

D O I：

10.1021/bi00384a003

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

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页码：2669 / 2673

页数：5

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共 22 条

[1] [Anonymous], MODERN THEORETICAL C
[2] [Anonymous], MOL DYNAMICS PROTEIN
[3] SITE-DIRECTED MUTAGENESIS AND THE ROLE OF THE OXYANION HOLE IN SUBTILISIN
BRYAN, P
PANTOLIANO, MW
QUILL, SG
HSIAO, HY
POULOS, T
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (11) : 3743 - 3745
[4] SN2 REACTION PROFILES IN THE GAS-PHASE AND AQUEOUS-SOLUTION
CHANDRASEKHAR, J
SMITH, SF
JORGENSEN, WL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (10) : 3049 - 3050
[5] MICROSCOPIC EXAMINATION OF FREE-ENERGY RELATIONSHIPS FOR ELECTRON-TRANSFER IN POLAR-SOLVENTS
HWANG, JK
WARSHEL, A
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (03) : 715 - 720
[6] CHEMICAL + ELECTROCHEMICAL ELECTRON-TRANSFER THEORY
MARCUS, RA
[J]. ANNUAL REVIEW OF PHYSICAL CHEMISTRY, 1964, 15 : 155 - &
[7] MONTE-CARLO DETERMINATION OF THE FREE-ENERGY AND INTERNAL ENERGY OF HYDRATION FOR THE ALA DIPEPTIDE AT 25-DEGREES-C
MEZEI, M
MEHROTRA, PK
BEVERIDGE, DL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (08) : 2239 - 2245
[8] PAULING L, 1946, CHEM ENG NEWS, V263, P294
[9] SUBTILISIN - STEREOCHEMICAL MECHANISM INVOLVING TRANSITION-STATE STABILIZATION
ROBERTUS, JD
ALDEN, RA
BIRKTOFT, JJ
KRAUT, J
[J]. BIOCHEMISTRY, 1972, 11 (23) : 4293 - &
[10] AN EMPIRICAL VALENCE BOND APPROACH FOR COMPARING REACTIONS IN SOLUTIONS AND IN ENZYMES
WARSHEL, A
WEISS, RM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (20) : 6218 - 6226