HIGHLY CONSERVED GENES-CODING FOR EUKARYOTIC TRANSLATION INITIATION-FACTOR EIF-4A OF TOBACCO HAVE SPECIFIC ALTERATIONS IN FUNCTIONAL MOTIFS

被引：10

作者：

BRANDER, KA

MANDEL, T

OWTTRIM, GW

KUHLEMEIER, C

机构：

[1] UNIV BERN,INST PLANT PHYSIOL,CH-3013 BERN,SWITZERLAND

[2] UNIV ALBERTA,DEPT MICROBIOL,EDMONTON,AB,CANADA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1261卷 / 03期

关键词：

RNA UNWINDING; RNA HELICASE; DEAD BOX PROTEIN; GENE FAMILY; (TOBACCO);

D O I：

10.1016/0167-4781(95)00052-I

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Eukaryotic translation initiation factor eIF-4A is an ATP-dependent RNA helicase that is required for the binding of mRNA to ribosomes. Plant eIF-4A-like proteins are highly homologous to eIF-4As from yeast, mouse and Drosophila melanogaster. The pattern of intron-exon boundaries in eIF-4A-like genes are conserved within tobacco, but are not conserved with other organisms. Fixed spacings between the functionally important sequence motifs, GKT-PTRELA (72 bp), DEAD-SAT (81 bp) and SAT-HRIGR (426 bp), are conserved between plants, mouse, Drosophila and yeast.

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页码：442 / 444

页数：3

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