BENZACRIDINES .6. FUNCTIONAL DERIVATIVES OF 5,6-DIMETHYLBENZ[C] ACRIDINE

被引:5
作者
CROMWELL, NH
NIELSEN, LA
机构
[1] Department of Chemistry, University of Nebraska, Lincoln, Nebraska
关键词
D O I
10.1002/jhet.5570060314
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
5,5‐Dimethyl‐5,6‐dihydrobenz[c]acridone has been synthesized by three different routes: a, from a condensation of anthranilic acid with 4,4‐dimethyl‐1‐tetraIone; b, by a catalytic hydrogenation of 2‐(o‐nitrobenzal)‐4,4‐dimethyl‐1‐tetralone oxide followed by an acid catalyzed cleavage of the oxide ring and closure of the nitrogen heterocyclic ring; c, a multi‐step process starting with 7‐carboxy‐5,5‐dimethyl‐5,6‐dihydrobenz[c]acridine. Several new functional derivatives of both 5,5‐dimethyl‐5,6‐dihydrobenz[c]acridine and of 5,6‐dimethylbenz[c]acridine were also produced for biological study by others. Copyright © 1969 Journal of Heterocyclic Chemistry
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页码:361 / &
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