BENZACRIDINES .6. FUNCTIONAL DERIVATIVES OF 5,6-DIMETHYLBENZ[C] ACRIDINE

被引：5

作者：

CROMWELL, NH

NIELSEN, LA

机构：

[1] Department of Chemistry, University of Nebraska, Lincoln, Nebraska

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1969年 / 6卷 / 03期

关键词：

D O I：

10.1002/jhet.5570060314

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5,5‐Dimethyl‐5,6‐dihydrobenz[c]acridone has been synthesized by three different routes: a, from a condensation of anthranilic acid with 4,4‐dimethyl‐1‐tetraIone; b, by a catalytic hydrogenation of 2‐(o‐nitrobenzal)‐4,4‐dimethyl‐1‐tetralone oxide followed by an acid catalyzed cleavage of the oxide ring and closure of the nitrogen heterocyclic ring; c, a multi‐step process starting with 7‐carboxy‐5,5‐dimethyl‐5,6‐dihydrobenz[c]acridine. Several new functional derivatives of both 5,5‐dimethyl‐5,6‐dihydrobenz[c]acridine and of 5,6‐dimethylbenz[c]acridine were also produced for biological study by others. Copyright © 1969 Journal of Heterocyclic Chemistry

引用

页码：361 / &

共 19 条

[11] CHARGE-TRANSFER COMPLEX FORMATION CARCINOGENICITY + PHOTODYNAMIC ACTIVITY IN POLYCYCLIC COMPOUNDS [J].